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研究人员测试杀死传播疟疾的蚊子的真菌

kira86 于2019-06-25发布 l 已有人浏览
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蚊子传播的疾病是导致非洲国家布基纳法索儿童死亡的主要原因,马里兰大学研究人员正在测试一种可以通过结出杀死蚊子的真菌。
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Researchers Test Fungus That Kills Malaria Mosquitos

研究人员测试杀死传播疟疾的蚊子的真菌

According to the severe malaria observatory, the mosquito-borne disease is the leading cause of child mortality in the African nation of Burkina Faso.It’s a loss no parent should have to suffer.“Losing a child was really painful for me or for any parent for that matter. So if we can find the solution against this disease which killed my child, other people we will think that they should do everything to eradicate this disease. They should help us. We are hoping we are happy without further prices gone.More than half of the world’s population is at risk of contracting the disease but it’s a unique problem in Africa and that’s where University of Maryland researchers are testing a fungus that kills mosquitoes on contact.“We took a gene from a spider and we put that spider gene which encodes an insect selective toxin. We put that gene into the fungus under the control of a promoter and the promoter is the on/off switch of a gene so under the control of this promoter which only turns on in insect blood.” The fungus works quickly and effectively on malaria carrying mosquitoes the moment it comes in contact with the insects.

根据严重疟疾观察站的数据,蚊子传播的疾病是导致非洲国家布基纳法索儿童死亡的主要原因。没有父母应该承受这种损失。失去一个孩子对我或任何父母来说都是非常痛苦的。所以,如果我们能找到治疗这个杀死我孩子的疾病的方法,其他人,我们会认为,他们应该尽一切努力根除这个疾病。他们应该帮助我们。我们希望不再付出代价,我们会很高兴。世界上一半以上的人口面临感染这种疾病的风险,但这在非洲是一个特有的问题,马里兰大学的研究人员在那里正在测试一种真菌,这种真菌可通过接触杀死蚊子。我们从蜘蛛身上提取了一个基因,然后把这个蜘蛛基因编码成一种昆虫选择性毒素。我们把这个基因放进一个启动子控制的真菌中,启动子是一个基因的开关,所以在这个启动子的控制下,这个启动子只在昆虫血液中启动。”这种真菌一旦接触到携带疟疾的蚊子,就会迅速有效地对它们起作用。

“Out of the box if they land anywhere on the outside of a mosquito they’ll recognize that they’re on a mosquito and they’ll burrow their way into the mosquito.”In tests once the fungus was introduced into a mosquito population the mosquitoes were gone in a month but success in the lab doesn’t mean success in the field so the team is testing their mosquito killing fungus in Burkina Faso with the help of researchers there.Using raw meat, the team attracts mosquitoes into these test rooms.Once inside they rest on a black cloth that has been treated with the fungus, the results are swift.“Well, basically within two generations we’ve killed 99 percent of the mosquitoes so we caused the mosquito population to collapse.”The researchers say that the dramatic results of their test and using their treatment belong with insecticides could have a big impact on fighting malaria and also can be adapted to fight other diseases like Zika or dengue.

当从盒子里出来,如果它们落在蚊子外面的任何地方,它们就会意识到它们落在蚊子身上,它们会钻入蚊子体内。”在测试中,一旦真菌被引入蚊子种群,蚊子在一个月内就消失了,但实验室的成功并不意味着在该领域的成功,因此研究小组正在布基纳法索的研究人员的帮助下在那里测试他们的杀蚊真菌。研究小组使用生肉将蚊子吸引到这些试验室,一旦蚊子进入试验室,它们就落在用真菌处理过的黑布上,结果很快就会出来。嗯,基本上在两代之内,我们已经杀死了百分之九十九的蚊子,所以我们使蚊子数量的暴跌。研究人员说,他们测试和使用杀虫剂治疗的激动人心的结果可能对防治疟疾产生重大影响,也可以适应于防治其他疾病,如齐卡或登革热。

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